Download e-book for kindle: A Practical Approach to Cardiovascular Medicine by Reza Ardehali, Marco Perez, Paul Wang

By Reza Ardehali, Marco Perez, Paul Wang

ISBN-10: 1405180390

ISBN-13: 9781405180399

Written, reviewed, and edited in a collaborative attempt by way of cardiology fellows and college of 1 of the main prestigious educational facilities within the kingdom, this concise quantity supplies cardiology fellows the publication they've got lengthy needed. Keeping insurance of the underlying pathophysiology and mechanism of illness to a minimal, the authors specialize in the analysis and therapy of cardiac problems. sensible and simply obtainable on the time of determination making, the booklet relays vital techniques via concise and to-the-point pearls and through the use of set of rules charts and illustrations.

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Additional resources for A Practical Approach to Cardiovascular Medicine

Example text

Goal: To evaluate if rosuvastatin therapy can reduce atheroma measured by intravascular ultrasound (IVUS). Method: Single-arm open label study involving 507 patients with baseline CAD as determined by IVUS who received rosuvastatin 40 mg/day for 2 years. Repeat IVUS measurements on 349 patients were performed 2 years later to evaluate atheroma size. Results: Rosuvastatin lowered LDL by 53% and increased HDL by 15%. Atheroma size decreased in 63% of patients and increased in 37% of patients. Take-home message: (Rosuva)statin therapy may decrease coronary atherosclerosis burden.

Results: Early invasive strategy: during hospitalization, increase in mortality; remainder of follow-up, decrease in mortality and in nonfatal MI; overall decrease in nonfatal MI. No decrease in death or MI in patients with negative TnI. Unstable Angina and Non-ST Elevation Myocardial Infarction 49 Take-home message: Routine invasive strategy was more beneficial in reducing MI, severe angina, and hospitalization when compared to selective invasive strategy. But note that the negative ICTUS study (no benefit for early invasive strategy in all patients with positive TnI) was performed after this meta-analysis.

Unstable Angina and Non-ST Elevation Myocardial Infarction 51 • Beta-blocker: • Indefinitely in all patients without contraindications • Long-term ACE-I or ARB: • HTN • DM • EF <40% • Consider ACE + ARB if persistent symptomatic CHF symptoms • CCB: • For ischemic symptoms if beta-blockers are contraindicated or ineffective • Lipids: • Begin statin therapy regardless of baseline level • Goal of therapy <70 mg/dL LDL • Consider adding fibrate or niacin if HDL<40 or TG >200 mg/dL • Other considerations: • Omega-3-fatty acid • Discontinue hormone replacement therapy in women after UA/NSTEMI • Discourage use of antioxidant supplements (vitamin C, E, folate).

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A Practical Approach to Cardiovascular Medicine by Reza Ardehali, Marco Perez, Paul Wang


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